Biomedical Journal of Indonesia

Spinal Instability in Myogenic Low Back Pain : Stabilization Exercise Approach

Awab Zakie Habibie — 2024-09-10

Spinal instability can be caused by various conditions including an illness, trauma, and degenerative processes affecting one or more of the three spinal subsystems. These three subsystems are the spine and ligaments, back muscles, and the nervous system work synergistically to maintain spinal stability. Until now it is still difficult to identify spinal instability. Low back pain (LBP) affects 60-80% of the world's population and in the United States causes losses of around $15-50 billion each year. For several decades, a muscle training program has been the main program that recommended to solve LBP, based on the premise that the muscle subsystem is a subsystem that can be repaired and improved, a muscle training program is developed and applied in the management of NPB. This literature review focuses on aspects of stabilization exercises in the management of low back pain with and without spinal instability.

Quintet Educational Cards on Breast Cancer Patients’ Knowledge Regarding Nutrition

Mutia Nadra Maulida — 2024-09-10

Introduction. Nutrition is important in undergoing treatment and healing process in breast cancer patients. The incidence of malnutrition and nutritional disorders in breast cancer patients reaches 35-70% of 72 breast cancer patients. One of the factors that can influence patients' attitudes toward managing nutrition in breast cancer patients is increasing knowledge through health education. This study aims to determine the effect of quintet card educational media on breast cancer patients' level of nutrition knowledge. Methods. This type of research is a quantitative pre-experimental study with a one-group pretest-posttest design. The population in this study was breast cancer patients in the Association for Supporting Women with Breast Cancer (ASWBC). The sample in this study consisted of 27 respondents. Sampling using a purposive sampling method. The statistical analysis used in this study is the marginal homogeneity test. Results. The analysis showed a p-value of 0.000 (α ≤ 0.05), which showed a significant difference in knowledge about nutrition in breast cancer patients before and after health education was carried out through the quintet card educational media. Nutrition knowledge is urgently needed by breast cancer patients and the quintet card educational media can be used as information material about nutrition in breast cancer patients and can be used in activities in the ASWBC. Conclusion. This educational media can be used by breast cancer patients following SOP as a play guide and as a media for health education.

The Relationship Between Personal Hygiene And The Incidence Of Pediculosis Capitis Among Students Of Sungai Beringin 02 Public Elementary School, District 50 Kota

Letvi Mona — 2024-09-10

Introduction. Pediculosis capitis or commonly known as head lice is a skin infection that attacks the human head. It is caused by the ectoparasite Pediculus Humanus Capitis, which lives by sucking blood on the scalp of infected people. One of the factors that can be related to pediculosis capitis is personal hygiene. The general objective of this research is to determine the relationship between personal hygiene and the incidence of pediculosis capitis in students at Sungai Beringin 02 Public Elementary School, Kabupaten 50 Kota. Methods. This research uses an analytical observational method with a cross-sectional approach, namely a study conducted to study the dynamics of the correlation between two variables. The accessible population in this research is all students of Sungai Beringin 02 Public Elementary School, Kabupaten 50 Kota in 2023. Results. This study shows 63.6% of students are not infested with pediculosis capitis. The highest class infested with pediculosis capitis is class 3-4, there are 50%, 95% of students who are infested with pediculosis capitis are female, and 65.5% of students have good personal hygiene. The results of the research show that there is a relationship between personal hygiene and the incidence of pediculosis capitis in students because 68.4% of students who are infested with pediculosis capitis do not have good personal hygiene. Conclusion. The results of bivariate analysis show that there is a significant relationship between the level of personal hygiene and the incidence of Pediculosis Capitis in students at Sungai Beringin 02 Public Elementary School with a p-value of 0.001.

The Relationship of Fat Intake and Body Fat Percentage in Medical Students

Nurul Yuli Permata Sari — 2024-09-10

Introduction. Obesity is an excessive fat accumulation in the body, now the prevalence is increasing in the group aged>18 years based on Body Mass Index (BMI). Nowadays body fat percentage has been declared to assess the risk factor of disease-related body weight better than BMI, people with proportioned weight had excessive body fat percentage evenly. Excessive fat intake is one of the important factors for obesity. The objective of this study was to analyze the association between fat intake with body fat percentage. Methods. This study was conducted with a cross-sectional design on 275 medical faculty students of Sriwijaya University, starting from August until December 2017 by collecting primary data through completing forms, food records, questionnaires, and physical examinations. Results. The results were analyzed statistically using chi-square. 67.3% of subjects had excessive body fat percentage and 50.2% with excessive fat intake. Results by the chi-square test indicate a negative association between fat intake with body fat percentage (p value=0.184). Conclusion. Fat intake with body fat percentage was negatively associated.

Knowledge And Perceptions of Nutrition and Weight Among First-Year Medical Students at Sriwijaya University

Mitha Ramadea — 2024-09-27

Introduction. Medical students of Sriwijaya University batch 2019 are new students who don’t have much knowledge about nutrition. In addition, new students also don’t know how to calculate Body Mass Index (BMI) through body height and weight. This study aimed to know the level of nutritional knowledge and the suitability of weight perception among the medical students of Sriwijaya University batch 2019. Methods. Descriptive research with a cross-sectional research design was conducted in Health Clinic UPT of Sriwijaya University and the Faculty of Medicine of Sriwijaya University in September 2019. The sample of this study was all medical students from Sriwijaya University batch 2019 who met the inclusion and exclusion criteria. The data was obtained through direct measurement and filling M-GNKQ questionnaire and weight perception questionnaire online. Results. In this study, 222 students met the inclusion and exclusion criteria, with 74 male students and 148 female students. As many as 70.7% of students have normal nutritional status. The average value of nutrition knowledge is 18.21 (45.5%) with the lowest value 0 and the highest value 32. Of all of the students, only 52.3% can perceive body weight correctly. The rest, as much as 33.3% is exaggerating perception and 14.4% is reducing perception. Conclusion. The knowledge of nutrition among the medical students of Sriwijaya University batch 2019 is still quite low and there are still many students who mistakenly perceive their weight.

Identifying Gene Variants That Are Pathogenic In Osteoporosis Using An Omics Data And Bioinformatics Approach

Danang Prasetyaning Amukti — 2024-10-18

Introduction. The biological cause of osteoporosis, a metabolic bone disease, is osteoclastic bone resorption that is not offset by osteoblastic bone synthesis. Fractures become more likely as a result of the bones being brittle and weak. Common genetic variants that indicate hereditary susceptibility factors to osteoporosis in the general population, as well as mutations affecting specific genes that cause uncommon monogenic causes of osteoporosis, are the two main types of osteoporosis. Bone defects can now be caused by numerous additional genes. In this study, we aimed to identify variants of this pathogen across continents using genome-based and bioinformatics methodologies. Methods. We integrated osteoporosis-associated variants into this study using various bioinformatics-based techniques by using GWAS data from the National Human Genome Research Institute (NHGRI). Results. We found that the variant rs3742909 is likely to cause osteoporosis. SMOC1 gene expression in whole blood tissue also appears to be affected by this variant. We found that this genomic variant requires additional research to validate functional and clinical studies in patients with osteoporosis. Conclusions. We suggest that better understanding of disease susceptibility, including osteoporosis, can be achieved through the merging of genome-based databases and bioinformatics. Our goal is to validate the findings of this study both in vitro and in vivo during the preclinical stage.

Comparative Evaluation of Electrochemiluminescence and Chemiluminescence Microparticle Immunoassays for Anti-Hepatitis C Virus (HCV) Detection

Phey Liana — 2024-10-29

Introduction. Anti-hepatitis C virus (HCV) testing is an immunological analysis designed to identify the presence of antibodies against the HCV antigen. This investigation is typically conducted using the chemiluminescence immunoassay (CLIA) technique, which yields precise results. Current research attempts to evaluate the outcomes of the anti-HCV test utilizing the Chemiluminescence Microparticle Immunoassay (CMIA) and the Electrochemiluminescence Immunoassay (ECLIA) approaches. Methods. This cross-sectional study comprised 63 serum samples collected via consecutive sampling. The acquired data were subjected to statistical analysis utilizing Cohen's Kappa agreement test. Results. Both immunoassay methods yielded identical results, indicating four reactive samples out of 63, equating to 6.35%. The agreement test result for the anti-HCV test was κ=1.000, signifying an almost perfect level of agreement. Conclusion. The anti-HCV assessment utilizing CMIA and ECLIA methodologies demonstrated near-perfect agreement. This signifies that these two procedures can be employed in clinical laboratories concurrently or interchangeably for the test.