Background: Primary CNS Lymphoma (PCNSL) is rare cancer from the brain or
spinal cord lymphatic tissue. The incidence increased in patients over 60 years, with
an incidence rate of 0.5/100,000 per year. PCNSL associated with poor survival. The
aim of the study was to determine the incidence of Brain Malignant Lymphoma based
on age, gender, symptoms, imaging modalities, HIV examination, and
histopathological results at dr. Kariadi Semarang.
Methods: This is a retrospective descriptive study. We collected brain malignant
lymphoma patient’s medical records who came to the ER and the Neurosurgery
Polyclinic of Dr. Kariadi Semarang from period January 2016-December 2018.
Results: There were 1,012 brain tumor patients, 6 patients were brain malignant
lymphoma with the highest prevalence in the age range of 45-65 years (5 patients)
and 66.67% male. The most common symptom was blurred vision 23.07%. The
imaging modalities showed lesions on: right parietal lobe 14.29%, sella region
14.29%, parasella region 14.29%, cerebellum 14.29%, IV ventricle 14.29%, vertebrae
sacrum 2-5 14.29 %, and the fronto-temporo-parietal region 14.29%. No HIV test
data were obtained. According to histopathology, Diffuse large B cell Lymphoma
Malignant non Germinal Center (DLBCL) and High grade, B cell Non Hodgkin
Lymphoma (small type) each were 33.33%.
Conclusions: The prevalence of malignant brain lymphoma cases was highest in the
45–65 year age group and male, with blurred vision. Most of the results of imaging
modalities show an even distribution of brain malignant lymphomas and generally
do not do HIV testing. The most common histopathological diagnosis was DLBCL