Chronic kidney disease (CKD) is associated with high mortality rates related to cardiovascular complications. Atherosclerosis, arteriosclerosis and vascular calcification conditions are often found in CKD patients. Carotid intima media thickness (cIMT) thickening is one of the parameters of vascular disorders. a cross sectional study was conducted on patients with chronic kidney disease in the Mohammad Hoesin hospital Palembang. Blood samples were examined in the hospital laboratory. CIMT thickening was examined using echocardiography. 55 patients with stage 3-5 of chronic kidney disease were examined. The median cIMT was 0.8 (0.6-1.45) mm. Spearman's correlation analysis showed a significant correlation between triglyceride levels and thickening of cIMT (r = 0.303, p = 0.025). A significant correlation was also shown between phosphate levels and cIMT thickening (r = 0.290, p = 0.032). There were significant correlations of triglyceride levels and phosphate levels on the thickening of cIMT in chronic kidney disease patients at Mohammad Hoesin Hospital Palembang.