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Nur Maziyah Hurin'in
Tri Yunita Fitria Damayanti
Nur Cholila
Gita Aprilia Ayu Masfufah
Tuadhatun Nuriyawati

Introduction. Nausea and vomiting are among the most common discomforts experienced by pregnant women in the first trimester, often leading to decreased nutritional intake, weight loss, and anemia, which may ultimately affect maternal and fetal health. Various complementary interventions, including acupressure, moxibustion, and ginger aromatherapy, have been developed as supportive therapies to reduce these symptoms. This aimed to analyze the effectiveness of PROMAMA is a combined intervention of acupressure, moxibustion, and ginger aromatherapy for nausea and vomiting of pregnancy in reducing nausea, vomiting, anxiety, and anemia, as well as improving weight gain. Methods. This quasi-experimental study employed a pre-test-post-test control group design with 120 first-trimester pregnant women who met the inclusion criteria. Participants were divided into three groups: control, Standard, and intensive intervention. Data were collected using the PUQE-24 (Pregnancy-Unique Quantification of Emesis and Nausea), GAD-7 (Generalized Anxiety Disorder-7), hemoglobin measurements, and maternal weight records. Statistical analyses included One-Way ANOVA, ANCOVA, and Independent Sample T-Test. Results. The findings revealed significant differences between the groups in reducing nausea and vomiting, anxiety, and hemoglobin levels at post-test 1 and post-test 2 (p < 0.05). Intensive interventions combining acupressure, moxibustion, and ginger aromatherapy showed greater effectiveness compared to Standard and control groups. However, no significant differences were observed in weight gain across the groups (p > 0.05). Conclusion. Acupressure, moxibustion, and ginger aromatherapy are effective for managing nausea, vomiting, anxiety, and anemia in first-trimester pregnant women. These interventions can be recommended as non-pharmacological approaches to improve maternal well-being and pregnancy outcomes.

Keywords: Wellbeing Nutritional needs Mental health Antenatal care
1. Hurin’in NM, Damayanti TYF, Cholila N. The Correlation of Information Media About Adolescent Anemia With Interest in Complementary or Pharmacology Therapy. Indones Midwifery Heal Sci J. 2022;6(3):266–73.
2. Usman H, Muliani M, Feby F, Nurfatimah N, Silfia NN. Efficacy of Pericardium 6 Acupressure in Reducing Nausea and Vomiting in First Trimester Pregnant Women. J Midwifery. 2024;9(2):6–11.
3. Devada AA, Kustiyati S. Pengaruh Terapi Akupresur Titik PC6 dan ST36 Dalam Mengurangi Mual Muntah Pada Ibu Hamil Trimester I. J Anestesi. 2024;2(3):156–67.
4. Putri GAAADH, Nurtini NM, Teja NMAYR. Efektivitas Aromaterapi Jahe terhadap Penurunan Mual Muntah Ibu Hamil: Studi Kuasi-Eksperimental. Bali Med J. 2024;11(1):54–64.
5. Panchal M, Rana P, Garg N, Dhankhar S, Sharma H, Chauhan S. A Comprehensive Review of Alternative Therapeutic Approaches for Nausea and Vomiting Relief in Pregnancy. New Emirates Med J. 2024;5.
6. Hurin’in NM, Damayanti TYF. Edukasi Pemanfaatan Terapi Komplementer Jahe dalam Asuhan Kebidanan untuk Mengurangi Mual Muntah Ibu Hamil. J Pengabdi Masy - PIMAS. 2023;2(1):59–66.
7. Chen L, Michalsen A. Management of chronic pain using complementary and integrative medicine. BMJ. 2017;357:j1284.
8. Wang X, Yang G, Li K, Yang F, Liang X, Wu S. Efficacy and safety of acupressure in nausea and vomiting during pregnancy: a systematic review and meta-analysis of randomized controlled trials. Arch Gynecol Obstet. 2024;309(4):1237–48.
9. Agustin N, Diana RN, Yusmanisari E, Hurin’in NM. Metodologi Penelitian Kesehatan. 1st ed. Alifba Media. Pamekasan: Alifba Media; 2025. 1–262 p.
10. Hu Y, Yang Q, Hu X. The efficacy and safety of acupuncture and moxibustion for the management of nausea and vomiting in pregnant women: A systematic review and meta-analysis. Heliyon. 2024;10(2):e24439.
11. Farlikhatun L, Rofiqoh LA. Pengaruh Akupresur Titik Perikardium 6 (Pc6) Terhadap Mual Muntah Pada Ibu Hamil Trimester I Di Pmb Maya Sofya Kotaagung. J Ilm Kesehat. 2025;14(1):73–9.
12. Rahmawati ESR, Qiftiyah MQ. The Impact of Pregnant Women Nutritional Status History With Stunting in Toddlers Aged 2-3 Years. Int J Midwifery Res. 2021;1(1):32–9.
13. Hurin’in NM, Putri FA, Puspitasari PN. “Bidankupedia” sebagai media e-health konsultasi tentang kesehatan reproduksi dan permasalahannya. ABDIMASNU: Jurnal Pengabdian kepada Masyarakat. 2021;1(2):49-54.
14. Sulistyowati R, Wulandari RCL. Literature Review: The Effect Of Lemon Aromatherapy On Emesis Gravidarum. Eduvest - J Univers Stud. 2021;1(9):931–42.
15. Fatmawati FD, Sulistyowati P, Astuti D. The Effect of Inhalation of Citrus Lemon Aromatherapy on the Degree of Nausea and Vomiting in Pregnant Women in Trimester I. Multidiscip Indones Cent J. 2025;2(3):3026–31.
16. Hurin’in NM. BIDANKUPEDIA: Mengenal Synapsin-I Dan Peran Maternal pada 1000 Hari Pertama Kehidupan. Rena Cipta Mandiri; 2023.
17. Hurin’in NM, Joewono HT, Widjiati W. Synapsin-I Expression in the Rattus norvegicus Pup’s Brain from Rat’s Maternal Death Model. Indian J Public Heal Res \& Dev. 2019;10(9).
18. Hurin’in NM, Afifah FEN. The Effect of Combination of Iron Tablet With Soybean Extract and Papaya on Hemoglobin Levels in Anemia Pregnant Women (in the Working Area of the Singgahan Public Health Center). 2nd Int Midwifery Webinar Res Find Dissem. 2023;249.
19. Jin B, Han Y, Jiang Y, Zhang J, Shen W, Zhang Y. Acupuncture for nausea and vomiting during pregnancy: A systematic review and meta-analysis. Complement Ther Med. 2024;85(8):103079
20. Putri RD, Astriana A, Natalia DA, Sari NE. Giving Aromatherapy Combination Of Lemon And Peppermint Affects The Intensity Of Nausea And Vomiting In Pregnant Women In Trimester I. J Kebidanan Malahayati. 2022;8(2):306–15.
21. Raihanah S, Djamil M, Jati SP. Moxibustion for nausea and vomiting in pregnancy. J Kedokt dan Kesehat Indones. 2020;11(1):67–72.
22. Rahma M, Rahayu YS. The impact of using acupressure wristband on PC 6 point to reduce nausea and vomiting during pregnancy. Malahayati Int J Nurs Heal Sci. 2024;7(1):112–20.
23. Sebayang WBR. Pengaruh Aromatherapy Terhadap Mual Muntah Dalam Kehamilan (Systematic Riview). J Ilm Kebidanan Imelda. 2021;7(2):65–8.
24. Hurin’in NM, Cholila N, Damayanti TYF. Acupressure, Moxibustion, and Aromatherapy for Nausea and Vomiting in First Trimester Pregnancy: A Literature Review on Potential Stunting Prevention from the Womb. Int J Midwifery Res. 2025;4(1):48–57.
25. Fitria A, Prawita AA, Yana S. Pengaruh Aromaterapi Lemon terhadap Emesis Gravidarum Trimester I. J Bidan Cerdas. 2021;3(3):96–102.
26. Sari BP, Yuniarti Y, Heryati K. The Effect of Lavender Aromatherapy in Reducing Emesis Gravidarum (First Trimester). J Kebidanan. 2023;13(1):27–33.
27. Ramin SM. ACOG Practice Bulletin No. 189 Summary: Nausea and Vomiting of Pregnancy. Obstet Gynecol. 2018;131(1):190–3.
28. Fejzo MS, Trovik J, Grooten IJ, Sridharan K, Roseboom TJ, Vikanes Å, et al. Nausea and vomiting of pregnancy and hyperemesis gravidarum. Nat Rev Dis Prim. 2019;5(1).
29. Cuffe JS, Xu ZC, Perkins A V. Biomarkers of oxidative stress in pregnancy complications. Biomark Med. 2017 Mar;11(3):295–306.
30. Parker SE, Van Bennekom C, Anderka M, Mitchell AA. Ondansetron for treatment of nausea and vomiting of pregnancy and the risk of specific birth defects. Obstet Gynecol. 2018;132(2):385–94.
31. Nafiah NAM, Chieng WK, Zainuddin AA, Chew KT, Kalok A, Abu MA, et al. Effect of Acupressure at P6 on Nausea and Vomiting in Women with Hyperemesis Gravidarum: A Randomized Controlled Trial. Int J Environ Res Public Health. 2022;19(17).